HitPredict

Interactor 1: CUBN (O60494)
Cubilin (460 kDa receptor) (Intestinal intrinsic factor receptor) (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor)
Gene: CUBN

Interactor 2: IF (P27352)
Cobalamin binding intrinsic factor (Gastric intrinsic factor) (Intrinsic factor) (IF) (INF)
Gene: CBLIF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.90	0.770

Property	Details
Experiments	9572993, 20237569
Identification Methods	pull down, x-ray crystallography, ion exchange chromatography, molecular sieving
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CUB~Cobalamin_bind
Common GO terms	GO:0005768 - endosome GO:0015889 - cobalamin transport GO:0016324 - apical plasma membrane GO:0031419 - cobalamin binding GO:0043202 - lysosomal lumen
Homologous interactions	0