Interactor 1: AURKB (O70126)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB
Interactor 2: Q921K2 (Q921K2)
Poly [ADP-ribose] polymerase (EC 2.4.2.30)
Gene: Parp1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 0.60 | 0.589 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16179389 |
| Identification Methods | affinity chromatography technology, pull down, far western blotting, enzymatic study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0034644 - cellular response to UV GO:0045824 - negative regulation of innate immune response GO:0160049 - negative regulation of cGAS/STING signaling pathway |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
