HitPredict

Interactor 1: LNX1 (O70263)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb protein X 1) (Ligand of Numb-binding protein 1) (Numb-binding protein 1) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Interactor 2: LIPA3 (P60469)
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)
Gene: Ppfia3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27889896
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~SAM_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 728 Mm			1 1194
+	Hs
		255251 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		LIPA3_HUMAN (1-1194): 1.64e-173: 546: 98.07
+	Mm
		71321 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		B2RXW8_MOUSE (1-1194): 8.29e-135: 443: 59.65
+	Mm
		400 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		A0A087WPM2_MOUSE (23-1178): 4.67e-131: 432: 57.90
+	Mm
		250638 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		LIPA2_MOUSE (1-1194): 2.43e-122: 410: 54.88
+	Hs
		1025322 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		LIPA1_HUMAN (1-1194): 2.26e-126: 419: 58.54
+	Rn
		957056 GRIP1_RAT (227-597): 2.67e-37: 152: 18.35		LIPA3_RAT (1-1194): 4.1e-171: 539: 98.83
+	Mm
		250623 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		KAZRN_MOUSE (406-1153): 1.21e-66: 243: 21.29
+	Rn
		957057 GRIP1_RAT (227-597): 2.67e-37: 152: 18.35		LIPA4_RAT (147-1178): 6.93e-126: 414: 55.79
+	Rn
		1265269 GRIP2_RAT (326-720): 7.34e-36: 147: 19.66		LIPA4_RAT (147-1178): 6.93e-126: 414: 55.79
+	Rn
		88835 GRIP1_RAT (227-597): 2.67e-37: 152: 18.35		D3ZZ81_RAT (1-1157): 2.27e-121: 406: 59.23
+	Mm
		1149111 LNX2_MOUSE (4-728): 1.69e-87: 291: 38.25		KAZRN_MOUSE (406-1153): 1.21e-66: 243: 21.29
+	Hs
		724926 LNX1_HUMAN (1-728): 2.56e-131: 407: 87.57		MYH9_HUMAN (339-955): 1.49e-20: 100: 10.37
+	Mm
		250641 LNX1_MOUSE (1-728): 1.2e-142: 437: 100.00		LIPB1_MOUSE (163-369): 2.75e-09: 63.6: 10.80
+	Hs
		1025339 GRIP2_HUMAN (314-495): 7.13e-09: 61.4: 21.13		LIPA1_HUMAN (1-1194): 2.26e-126: 419: 58.54
+	Hs
		1202996 PARD3_HUMAN (131-652): 4.36e-20: 97.8: 12.59		LIPB1_HUMAN (267-1139): 1.58e-70: 258: 18.20