HitPredict

Interactor 1: ATX2 (O70305)
Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog)
Gene: Atxn2

Interactor 2: FUS (P56959)
RNA-binding protein FUS (Protein pigpen)
Gene: FUS

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	23681068
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1285 Mm			1 518
+	Hs
		1305733 ATX2_HUMAN (75-1285): 1.06e-107: 372: 87.47		RBM8A_HUMAN (238-359): 1.45e-23: 99.2: 29.51
+	Hs
		1031438 ATX2_HUMAN (75-1285): 1.06e-107: 372: 87.47		PABP4_HUMAN (274-372): 4.92e-13: 73.6: 22.22
+	Hs
		516661 ATX2_HUMAN (75-1285): 1.06e-107: 372: 87.47		PABP1_HUMAN (269-372): 1.46e-11: 69: 21.15
+	Hs
		516595 KMT2C_HUMAN (415-1281): 3.57e-69: 259: 15.03		PABP1_HUMAN (269-372): 1.46e-11: 69: 21.15
+	Hs
		726955 ATX2L_HUMAN (6-720): 1.88e-14: 80.9: 12.43		FUS_HUMAN (1-518): 1.02e-35: 141: 84.82
+	Hs
		967541 PCLO_HUMAN (742-1284): 2.59e-18: 94: 9.32		EWS_HUMAN (3-444): 5.23e-30: 126: 34.13
+	At
		790113 CID4_ARATH (196-754): 1.33e-35: 146: 15.94		PABP2_ARATH (251-374): 2.1e-12: 71.6: 21.43
+	Hs
		726817 MDC1_HUMAN (576-1284): 6.74e-13: 76.1: 8.73		FUS_HUMAN (1-518): 1.02e-35: 141: 84.82
+	At
		1277466 CID4_ARATH (196-754): 1.33e-35: 146: 15.94		PABP8_ARATH (280-372): 4.17e-10: 64.3: 20.43
+	Hs
		967173 MDC1_HUMAN (576-1284): 6.74e-13: 76.1: 8.73		EWS_HUMAN (3-444): 5.23e-30: 126: 34.13
+	Hs
		124053 CIC_HUMAN (140-1152): 2.09e-09: 64.3: 9.71		SPT5H_HUMAN (15-228): 1.41e-31: 131: 15.81
+	Hs
		967303 TITIN_HUMAN (117-1244): 1.4e-09: 65.1: 7.84		EWS_HUMAN (3-444): 5.23e-30: 126: 34.13
+	Hs
		967374 CIC_HUMAN (140-1152): 2.09e-09: 64.3: 9.71		EWS_HUMAN (3-444): 5.23e-30: 126: 34.13
+	Hs
		1031402 ATX2L_HUMAN (6-720): 1.88e-14: 80.9: 12.43		PABP4_HUMAN (274-372): 4.92e-13: 73.6: 22.22
+	Hs
		516606 ATX2L_HUMAN (6-720): 1.88e-14: 80.9: 12.43		PABP1_HUMAN (269-372): 1.46e-11: 69: 21.15
+	Hs
		1031405 TITIN_HUMAN (117-1244): 1.4e-09: 65.1: 7.84		PABP4_HUMAN (274-372): 4.92e-13: 73.6: 22.22
+	Hs
		516609 TITIN_HUMAN (117-1244): 1.4e-09: 65.1: 7.84		PABP1_HUMAN (269-372): 1.46e-11: 69: 21.15
+	Hs
		867119 CIC_HUMAN (140-1152): 2.09e-09: 64.3: 9.71		SC24C_HUMAN (30-289): 1.74e-10: 65.9: 13.46
+	Hs
		965152 ANK2_HUMAN (79-835): 1.34e-09: 65.1: 9.94		PABP3_HUMAN (269-372): 4.42e-10: 64.3: 19.23