HitPredict

Interactor 1: E41L2 (O70318)
Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G)
Gene: Epb41l2

Interactor 2: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0008360 - regulation of cell shape GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 988 Mm			1 192
+	Hs
		925613 E41L1_HUMAN (145-988): 0: 549: 42.48		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564684 E41L1_HUMAN (145-988): 0: 549: 42.48		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545616 E41L1_HUMAN (145-988): 0: 549: 42.48		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		1330914 E41L1_HUMAN (145-988): 0: 549: 42.48		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892594 E41L1_HUMAN (145-988): 0: 549: 42.48		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		951337 E41L1_HUMAN (145-988): 0: 549: 42.48		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		894429 E41L1_HUMAN (145-988): 0: 549: 42.48		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900899 E41L1_HUMAN (145-988): 0: 549: 42.48		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436506 E41L1_HUMAN (145-988): 0: 549: 42.48		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		925637 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564694 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545630 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		1330927 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892609 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		951359 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		894461 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900931 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436519 E41L5_HUMAN (166-857): 2.05e-150: 465: 25.78		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		894040 PTN14_HUMAN (194-898): 5.02e-132: 429: 17.82		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900503 PTN14_HUMAN (194-898): 5.02e-132: 429: 17.82		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98