HitPredict

Interactor 1: 1433S (O70456)
14-3-3 protein sigma (Stratifin)
Gene: Sfn

Interactor 2: LMNA (P48678)
Prelamin-A/C [Cleaved into: Lamin-A/C]
Gene: LMNA

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21327095
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Mm			1 665
+	Hs
		380460 1433Z_HUMAN (1-239): 9.5e-105: 305: 72.39		K2C6B_HUMAN (24-407): 1.05e-117: 364: 24.03
+	Hs
		359676 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		LMNA_HUMAN (1-665): 8.09e-72: 247: 96.10
+	Hs
		443357 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		VIME_HUMAN (27-389): 6.82e-31: 128: 29.20
+	Hs
		359838 1433Z_HUMAN (1-239): 9.5e-105: 305: 72.39		LMNA_HUMAN (1-665): 8.09e-72: 247: 96.10
+	Hs
		443445 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		VIME_HUMAN (27-389): 6.82e-31: 128: 29.20
+	Mm
		821702 1433G_MOUSE (1-242): 5.04e-98: 288: 64.75		LMNA_MOUSE (1-665): 1.31e-71: 246: 100.00
+	Mm
		372933 1433Z_MOUSE (1-242): 1.18e-136: 385: 70.66		GFAP_MOUSE (27-427): 9.7e-30: 124: 28.68
+	Hs
		595099 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		LMNB1_HUMAN (12-548): 1.64e-47: 178: 56.69
+	Hs
		595184 1433Z_HUMAN (1-239): 9.5e-105: 305: 72.39		LMNB1_HUMAN (12-548): 1.64e-47: 178: 56.69
+	Hs
		904437 1433G_HUMAN (1-242): 5.04e-98: 288: 64.75		KRT85_HUMAN (23-389): 9.22e-49: 180: 24.52
+	Hs
		905163 1433G_HUMAN (1-242): 5.04e-98: 288: 64.75		KRT82_HUMAN (25-389): 1.07e-44: 169: 24.66
+	Hs
		443346 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		VIME_HUMAN (27-389): 6.82e-31: 128: 29.20
+	Hs
		904944 1433G_HUMAN (1-242): 5.04e-98: 288: 64.75		KRT35_HUMAN (30-387): 1.56e-39: 153: 25.14
+	Hs
		569050 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		DESM_HUMAN (27-389): 5.64e-28: 119: 30.30
+	Hs
		443452 1433Z_HUMAN (1-239): 9.5e-105: 305: 72.39		VIME_HUMAN (27-389): 6.82e-31: 128: 29.20
+	Hs
		569067 1433Z_HUMAN (1-239): 9.5e-105: 305: 72.39		DESM_HUMAN (27-389): 5.64e-28: 119: 30.30
+	Rn
		677657 1433B_RAT (1-239): 2.55e-99: 291: 68.62		VIME_RAT (27-389): 3.28e-31: 129: 29.20
+	Hs
		443356 1433B_HUMAN (1-239): 1.59e-99: 291: 68.20		VIME_HUMAN (27-389): 6.82e-31: 128: 29.20
+	Hs
		443441 1433G_HUMAN (1-242): 5.04e-98: 288: 64.75		VIME_HUMAN (27-389): 6.82e-31: 128: 29.20
+	Hs
		422160 1433G_HUMAN (1-242): 5.04e-98: 288: 64.75		NFL_HUMAN (28-433): 1.2e-26: 116: 27.56