HitPredict

Interactor 1: EFNB2 (O73874)
Ephrin-B2a
Gene: efnb2a

Interactor 2: Q5ZEW1 (Q5ZEW1)
receptor protein-tyrosine kinase (EC 2.7.10.1)
Gene: epha4a

Species: Danio rerio

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26190107
Identification Methods	avexis
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ephrin~Ephrin_lbd
Common GO terms	GO:0005886 - plasma membrane GO:0007411 - axon guidance
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 332 Dr			1 986
+	Hs
		856510 EFNB2_HUMAN (3-332): 8.51e-165: 464: 65.56		EPHA4_HUMAN (1-986): 0: 1220: 82.27
+	Mm
		856591 EFNB2_MOUSE (3-332): 1.41e-165: 466: 65.56		EPHA4_MOUSE (1-986): 0: 1214: 82.17
+	Hs
		957840 EFNB1_HUMAN (6-332): 7.83e-165: 464: 51.01		EPHA7_HUMAN (6-986): 0: 1174: 61.71
+	Dr
		47564 EFNB2_DANRE (1-332): 2.14e-165: 465: 100.00		A0A8M9PHF0_DANRE (10-986): 0: 1157: 61.24
+	Hs
		856508 EFNB2_HUMAN (3-332): 8.51e-165: 464: 65.56		EPHA5_HUMAN (2-986): 0: 1154: 62.69
+	Hs
		665381 EFNB2_HUMAN (3-332): 8.51e-165: 464: 65.56		EPHA3_HUMAN (26-986): 0: 1143: 61.76
+	Hs
		665390 EFNB1_HUMAN (6-332): 7.83e-165: 464: 51.01		EPHA3_HUMAN (26-986): 0: 1143: 61.76
+	Hs
		665565 EFNB2_HUMAN (3-332): 8.51e-165: 464: 65.56		EPHB2_HUMAN (30-986): 0: 1140: 58.13
+	Hs
		665579 EFNB1_HUMAN (6-332): 7.83e-165: 464: 51.01		EPHB2_HUMAN (30-986): 0: 1140: 58.13
+	Mm
		856589 EFNB2_MOUSE (3-332): 1.41e-165: 466: 65.56		EPHB2_MOUSE (30-981): 0: 1137: 58.39
+	Rn
		454786 Q6P7B6_RAT (6-332): 1.16e-163: 461: 50.87		EPHB1_RAT (23-983): 0: 1140: 58.62
+	Dr
		140382 EFNB2_DANRE (1-332): 2.14e-165: 465: 100.00		EPHA3_DANRE (3-975): 0: 1135: 61.56
+	Mm
		856588 EFNB2_MOUSE (3-332): 1.41e-165: 466: 65.56		EPHB3_MOUSE (28-980): 0: 1071: 56.14
+	Hs
		856507 EFNB2_HUMAN (3-332): 8.51e-165: 464: 65.56		EPHB3_HUMAN (27-980): 0: 1067: 56.26
+	Hs
		872403 EFNB1_HUMAN (6-332): 7.83e-165: 464: 51.01		EPHB3_HUMAN (27-980): 0: 1067: 56.26
+	Hs
		856509 EFNB2_HUMAN (3-332): 8.51e-165: 464: 65.56		EPHB4_HUMAN (14-977): 0: 1011: 50.36
+	Dr
		251123 EFNB2_DANRE (1-332): 2.14e-165: 465: 100.00		EPB4B_DANRE (10-980): 0: 1003: 50.20
+	Dr
		251122 EFNB2_DANRE (1-332): 2.14e-165: 465: 100.00		EPB4A_DANRE (15-981): 0: 994: 49.95
+	Dr
		47540 EFNB2_DANRE (1-332): 2.14e-165: 465: 100.00		A0A8M3AP95_DANRE (10-627): 0: 659: 46.81
+	Hs
		674396 EFNB1_HUMAN (6-332): 7.83e-165: 464: 51.01		UFO_HUMAN (294-917): 1.32e-150: 470: 26.11