Interactor 1: GMDS (O60547)
GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)
Gene: GMDS
Interactor 2: GMDS (O60547)
GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)
Gene: GMDS
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.85 | 1.00 | 0.927 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 16189514, 32296183, 31515488, unassigned1304 |
| Identification Methods | two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GDP_Man_Dehyd~GDP_Man_Dehyd |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007219 - Notch signaling pathway GO:0008446 - GDP-mannose 4,6-dehydratase activity GO:0019673 - GDP-mannose metabolic process and 4 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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| + | Ce | |
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| + | At | |
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| + | Hs | |
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| + | Dm | |
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| + | Sc | |
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| + | Ec | |
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| + | Cj | |
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| + | Ec | |
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| + | At |  |
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
