Interactor 1: ABCB7 (O75027)
Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein)
Gene: ABCB7

Interactor 2: HEMH (P22830)
Ferrochelatase, mitochondrial (EC 4.98.1.1) (Heme synthase) (Protoheme ferro-lyase)
Gene: FECH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.655

The method score is based on:

Property Details
Experiments 12480705, 30765471
Identification Methods pull down, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, comigration in non denaturing gel electrophoresis
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0042803 - protein homodimerization activity
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 752
Hs

1 423
+ Mm
+ Hs

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Last updated: 15 Jul 2024