HitPredict

Interactor 1: ABCB7 (O75027)
Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein)
Gene: ABCB7

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1903427 - negative regulation of reactive oxygen species biosynthetic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 752 Hs			1 193
+	Hs
		252822 ABCB7_HUMAN (1-752): 0: 608: 100.00		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		252817 ABCB7_HUMAN (1-752): 0: 608: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		252800 ABCB7_HUMAN (1-752): 0: 608: 100.00		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		252820 ABCB7_HUMAN (1-752): 0: 608: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		925651 ABCBA_HUMAN (136-709): 1.19e-158: 479: 26.60		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		545640 ABCBA_HUMAN (136-709): 1.19e-158: 479: 26.60		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Sc
		419697 YCFI_YEAST (37-718): 2.02e-58: 217: 15.62		RHO1_YEAST (3-188): 1.51e-97: 283: 73.12
+	Hs
		706695 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		706702 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436176 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		706705 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		706693 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545225 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		706692 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		706700 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120319 MRP1_HUMAN (46-747): 9.82e-65: 236: 18.63		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		179391 MRP5_HUMAN (73-745): 1.64e-46: 181: 14.48		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		179393 MRP5_HUMAN (73-745): 1.64e-46: 181: 14.48		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		179400 MRP5_HUMAN (73-745): 1.64e-46: 181: 14.48		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		120217 MRP5_HUMAN (73-745): 1.64e-46: 181: 14.48		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98