HitPredict

Interactor 1: MITF (O75030)
Microphthalmia-associated transcription factor (Class E basic helix-loop-helix protein 32) (bHLHe32)
Gene: MITF

Interactor 2: TFEB (P19484)
Transcription factor EB (Class E basic helix-loop-helix protein 35) (bHLHe35)
Gene: TFEB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.903

The method score is based on:

Property Details
Experiments 28514442, 33961781, 26496610, 15507434
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 526
Hs

1 476
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024