HitPredict

Interactor 1: MITF (O75030)
Microphthalmia-associated transcription factor (Class E basic helix-loop-helix protein 32) (bHLHe32)
Gene: MITF

Interactor 2: TFE3 (P19532)
Transcription factor E3 (Class E basic helix-loop-helix protein 33) (bHLHe33)
Gene: TFE3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 28514442, 33961781, 11818452, 15507434
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 8 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 526
Hs

1 575
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024