HitPredict

Interactor 1: PLXA2 (O75051)
Plexin-A2 (Semaphorin receptor OCT)
Gene: PLXNA2

Interactor 2: DQA1 (P01909)
HLA class II histocompatibility antigen, DQ alpha 1 chain (DC-1 alpha chain) (DC-alpha) (HLA-DCA) (MHC class II DQA1)
Gene: HLA-DQA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1894 Hs			1 254
+	Hs
		354905 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		DQA1_HUMAN (1-254): 4.92e-93: 275: 100.00
+	Hs
		354787 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		DRA_HUMAN (1-254): 3.02e-80: 243: 52.94
+	Hs
		382644 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		DPB1_HUMAN (5-248): 2.08e-78: 238: 22.93
+	Hs
		570384 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		HLAG_HUMAN (15-246): 2.47e-76: 236: 15.04
+	Hs
		354823 PLXA3_HUMAN (29-1894): 0: 2407: 59.89		DQA1_HUMAN (1-254): 4.92e-93: 275: 100.00
+	Hs
		570313 PLXA3_HUMAN (29-1894): 0: 2407: 59.89		HLAG_HUMAN (15-246): 2.47e-76: 236: 15.04
+	Hs
		165158 PLXB2_HUMAN (36-1891): 0: 1941: 32.04		HLAG_HUMAN (15-246): 2.47e-76: 236: 15.04
+	Hs
		354896 SEM4B_HUMAN (27-596): 6.1e-125: 416: 16.83		DQA1_HUMAN (1-254): 4.92e-93: 275: 100.00
+	Hs
		320755 SEM4F_HUMAN (3-624): 1.38e-123: 410: 14.97		DQA1_HUMAN (1-254): 4.92e-93: 275: 100.00
+	Hs
		354890 SEM4C_HUMAN (42-579): 9.89e-122: 407: 16.38		DQA1_HUMAN (1-254): 4.92e-93: 275: 100.00
+	Hs
		354776 SEM4G_HUMAN (5-537): 1.69e-121: 406: 18.36		DRA_HUMAN (1-254): 3.02e-80: 243: 52.94
+	Hs
		570377 SEM4G_HUMAN (5-537): 1.69e-121: 406: 18.36		HLAG_HUMAN (15-246): 2.47e-76: 236: 15.04
+	Hs
		234723 PLXC1_HUMAN (62-912): 3.36e-104: 371: 18.14		DPA1_HUMAN (1-254): 3.53e-83: 251: 57.65
+	Hs
		382272 MET_HUMAN (809-1205): 9.08e-101: 358: 25.93		HLAA_HUMAN (15-251): 9.15e-85: 258: 15.94
+	Hs
		441407 MET_HUMAN (809-1205): 9.08e-101: 358: 25.93		HLAC_HUMAN (15-216): 8.79e-77: 238: 17.29
+	Hs
		320757 SEM4F_HUMAN (3-624): 1.38e-123: 410: 14.97		DQB1_HUMAN (12-218): 4.83e-55: 179: 20.55
+	Hs
		320756 SEM4F_HUMAN (3-624): 1.38e-123: 410: 14.97		DRB1_HUMAN (48-218): 5.78e-52: 171: 23.16
+	Hs
		320767 SEM4F_HUMAN (3-624): 1.38e-123: 410: 14.97		DRB3_HUMAN (91-218): 1.75e-50: 167: 25.78
+	Hs
		354945 RON_HUMAN (810-1205): 1.3e-87: 318: 23.37		DRB1_HUMAN (48-218): 5.78e-52: 171: 23.16