HitPredict

Interactor 1: PLXA2 (O75051)
Plexin-A2 (Semaphorin receptor OCT)
Gene: PLXNA2

Interactor 2: NKG2A (P26715)
NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a)
Gene: KLRC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1894 Hs			1 233
+	Hs
		253468 PLXA2_HUMAN (1-1894): 0: 2664: 100.00		CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01
+	Hs
		253509 PLXA2_HUMAN (1-1894): 0: 2664: 100.00		CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81
+	Hs
		644655 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00
+	Hs
		644548 PLXA3_HUMAN (29-1894): 0: 2407: 59.89		NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00
+	Hs
		1100817 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01
+	Hs
		1329769 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		CLC4M_HUMAN (95-232): 4.96e-43: 151: 21.48
+	Hs
		1028535 PLXA1_HUMAN (8-1894): 0: 2455: 63.51		KLRD1_HUMAN (69-233): 1.35e-43: 146: 32.35
+	Hs
		850476 PLXA3_HUMAN (29-1894): 0: 2407: 59.89		CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01
+	Hs
		850489 PLXA3_HUMAN (29-1894): 0: 2407: 59.89		CLC2B_HUMAN (80-233): 3.14e-40: 137: 25.64
+	Hs
		165162 PLXB2_HUMAN (36-1891): 0: 1941: 32.04		NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00
+	Hs
		165206 PLXB2_HUMAN (36-1891): 0: 1941: 32.04		CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01
+	Hs
		165230 PLXB2_HUMAN (36-1891): 0: 1941: 32.04		CLC2B_HUMAN (80-233): 3.14e-40: 137: 25.64
+	Hs
		320760 SEM4F_HUMAN (3-624): 1.38e-123: 410: 14.97		NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00
+	Hs
		644615 SEM4D_HUMAN (16-563): 3.7e-117: 395: 16.72		NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00
+	Hs
		1027979 SEM3B_HUMAN (21-543): 1.63e-121: 404: 18.79		PGCB_HUMAN (12-233): 5.18e-51: 179: 18.64
+	Hs
		320771 SEM4F_HUMAN (3-624): 1.38e-123: 410: 14.97		CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01
+	Hs
		320781 SEM4F_HUMAN (3-624): 1.38e-123: 410: 14.97		CLC2D_HUMAN (51-231): 6.82e-43: 145: 21.28
+	Hs
		1100777 SEM4D_HUMAN (16-563): 3.7e-117: 395: 16.72		CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01
+	Hs
		441544 MET_HUMAN (809-1205): 9.08e-101: 358: 25.93		CLC4D_HUMAN (53-232): 2.6e-40: 139: 15.24
+	Hs
		981902 RON_HUMAN (810-1205): 1.3e-87: 318: 23.37		CLC2B_HUMAN (80-233): 3.14e-40: 137: 25.64