HitPredict

Interactor 1: LRP4 (O75096)
Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)
Gene: LRP4

Interactor 2: ZN398 (Q8TD17)
Zinc finger protein 398 (Zinc finger DNA-binding protein p52/p71)
Gene: ZNF398

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1905 Hs			1 642
+	Hs
		254278 LRP4_HUMAN (1-1905): 0: 2150: 100.00		ZN383_HUMAN (435-639): 2.95e-99: 313: 35.12
+	Hs
		254261 LRP4_HUMAN (1-1905): 0: 2150: 100.00		ZNF74_HUMAN (184-454): 6.23e-78: 262: 18.40
+	Hs
		254270 LRP4_HUMAN (1-1905): 0: 2150: 100.00		Z354C_HUMAN (517-615): 5.64e-25: 111: 34.34
+	Hs
		254273 LRP4_HUMAN (1-1905): 0: 2150: 100.00		ZNF34_HUMAN (184-314): 2.59e-15: 81: 7.53
+	Hs
		200259 SORL_HUMAN (1615-1724): 2e-10: 68.6: 10.81		ZN264_HUMAN (181-623): 5.41e-167: 493: 25.44
+	Hs
		200250 LRP2_HUMAN (273-499): 9.34e-10: 66.3: 15.45		ZN264_HUMAN (181-623): 5.41e-167: 493: 25.44
+	Hs
		258331 LRP5_HUMAN (269-451): 2.18e-10: 68.2: 17.84		ZN383_HUMAN (435-639): 2.95e-99: 313: 35.12
+	Hs
		270315 LRP6_HUMAN (269-440): 1.59e-09: 65.5: 19.21		ZN383_HUMAN (435-639): 2.95e-99: 313: 35.12
+	Hs
		1083635 SORL_HUMAN (1615-1724): 2e-10: 68.6: 10.81		ZNF74_HUMAN (184-454): 6.23e-78: 262: 18.40
+	Hs
		1048412 NID2_HUMAN (7-314): 5.72e-13: 76.7: 12.50		ZN774_HUMAN (367-592): 5.56e-53: 191: 42.04
+	Hs
		1269039 SORL_HUMAN (1615-1724): 2e-10: 68.6: 10.81		ZN777_HUMAN (474-637): 7.73e-47: 179: 31.50
+	Hs
		1060253 SORL_HUMAN (1615-1724): 2e-10: 68.6: 10.81		ZN169_HUMAN (339-568): 1.58e-47: 178: 38.10
+	Hs
		1060268 LRP1B_HUMAN (251-512): 5.06e-10: 67.4: 13.26		ZN169_HUMAN (339-568): 1.58e-47: 178: 38.10
+	Hs
		1205167 SORL_HUMAN (1615-1724): 2e-10: 68.6: 10.81		Z354C_HUMAN (517-615): 5.64e-25: 111: 34.34
+	Hs
		1223925 SORL_HUMAN (1615-1724): 2e-10: 68.6: 10.81		ZNF34_HUMAN (184-314): 2.59e-15: 81: 7.53