Interactor 1: ROCK2 (O75116)
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)
Gene: ROCK2

Interactor 2: MLRV (P10916)
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Cardiac myosin light chain 2) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v) (Ventricular myosin light chain 2)
Gene: MYL2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 25412762
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1388
Hs

1 166
+ Dm
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Hs
+ At
+ At
+ At
+ At
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024