HitPredict

Interactor 1: ROCK2 (O75116)
Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho kinase 2) (Rho-associated, coiled-coil-containing protein kinase 2) (Rho-associated, coiled-coil-containing protein kinase II) (ROCK-II) (p164 ROCK-2)
Gene: ROCK2

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32687490
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1388 Hs			1 646
+	Hs
		504029 ROCK1_HUMAN (18-1383): 0: 667: 64.67		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		504896 KS6B2_HUMAN (86-445): 2.04e-120: 386: 31.52		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		564201 KS6B2_HUMAN (86-445): 2.04e-120: 386: 31.52		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		483772 ST38L_HUMAN (74-417): 1.07e-79: 272: 40.47		HS71A_HUMAN (1-646): 0: 948: 84.37
+	Hs
		148327 CTRO_HUMAN (329-921): 4.6e-23: 109: 12.00		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		148449 CTRO_HUMAN (329-921): 4.6e-23: 109: 12.00		HS71L_HUMAN (2-646): 0: 966: 82.48
+	Hs
		504240 MRCKG_HUMAN (541-917): 1e-21: 104: 14.39		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		148367 CTRO_HUMAN (329-921): 4.6e-23: 109: 12.00		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		148576 CTRO_HUMAN (329-921): 4.6e-23: 109: 12.00		HSP72_HUMAN (2-646): 0: 940: 85.47