Interactor 1: ICOSL (O75144)
ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)
Gene: ICOSLG

Interactor 2: ICOS (Q9Y6W8)
Inducible T-cell costimulator (Activation-inducible lymphocyte immunomediatory molecule) (CD antigen CD278)
Gene: ICOS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.880

The method score is based on:

Property Details
Experiments 28514442, 11956294, 16951355
Identification Methods affinity chromatography technology, pull down, enzyme linked immunosorbent assay, surface plasmon resonance, fluorescence-activated cell sorting, far western blotting, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains V-set~V-set_2
Common GO terms GO:0005886 - plasma membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 302
Hs

1 199
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024