HitPredict

Interactor 1: HIP1R (O75146)
Huntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12)
Gene: HIP1R

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007015 - actin filament organization GO:0043065 - positive regulation of apoptotic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1068 Hs			1 196
+	Hs
		124392 HIP1_HUMAN (1-1037): 2.22e-63: 235: 49.57		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		124390 HIP1_HUMAN (1-1037): 2.22e-63: 235: 49.57		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545719 TLN2_HUMAN (292-1010): 1.15e-46: 185: 16.58		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Dm
		114274 M9PBW9_DROME (497-1024): 1.38e-34: 146: 18.44		RAC1_DROME (1-196): 1.58e-77: 231: 53.06
+	Dm
		776919 Q9VSL8_DROME (497-1024): 1.69e-34: 146: 18.44		RAC1_DROME (1-196): 1.58e-77: 231: 53.06
+	Hs
		724757 MYH9_HUMAN (709-1068): 7.71e-17: 88.3: 9.44		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		724776 MYH9_HUMAN (709-1068): 7.71e-17: 88.3: 9.44		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		725138 MYH10_HUMAN (370-811): 7.9e-10: 65.7: 14.22		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		725125 MYH10_HUMAN (370-811): 7.9e-10: 65.7: 14.22		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49