HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.660

The method score is based on:

Property Details
Experiments 25416956, 27569044, 10944455
Identification Methods two hybrid, pull down, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
and 10 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1001
Hs

1 1001
+ At
+ Hs
+ Hs
+ Sc
+ At
+ Hs
+ Hs
+ Os
+ Hs
+ Dm
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024