HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042803 - protein homodimerization activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 796
+	Hs
		384983 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384384 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		608006 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59
+	Hs
		384385 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384113 LAMB1_HUMAN (82-412): 8.06e-19: 94.7: 12.65		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384210 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		665375 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		EPHA3_HUMAN (262-788): 8.75e-112: 365: 26.64
+	Rn
		94275 F1LUA1_RAT (81-980): 3.4e-36: 150: 10.58		INSR_RAT (493-777): 7.31e-66: 241: 41.95
+	Hs
		725069 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		ALK_HUMAN (505-790): 8.72e-63: 231: 42.07
+	Hs
		725268 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		ALK_HUMAN (505-790): 8.72e-63: 231: 42.07