HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	33640491, 34585037, 35785414, 22155569
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 920
+	Hs
		487507 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		487183 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		487105 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		256196 BRE1B_HUMAN (1-1001): 5.92e-75: 268: 100.00		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		369096 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		368902 MYH6_HUMAN (461-982): 5.68e-20: 98.6: 9.77		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		377795 MYH2_HUMAN (291-983): 3.18e-32: 138: 9.47		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		587127 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		RXRA_HUMAN (392-902): 7.05e-120: 374: 19.84
+	Hs
		724944 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		148263 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		368926 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		433179 LAMB1_HUMAN (82-412): 8.06e-19: 94.7: 12.65		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		1269900 MYH13_HUMAN (493-982): 2.93e-16: 86.3: 6.99		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		1270044 MYH4_HUMAN (567-982): 2.09e-15: 83.6: 9.20		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		377068 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		522631 MYH7_HUMAN (1-380): 1.19e-11: 71.3: 11.54		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		149132 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		551794 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		414434 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		PRGR_HUMAN (469-920): 4.71e-106: 352: 45.73