HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26269332
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043005 - neuron projection
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 758
+	Hs
		497769 MYH2_HUMAN (291-983): 3.18e-32: 138: 9.47		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496438 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496439 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582036 MYH10_RAT (2-612): 2.5e-23: 109: 12.42		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94262 MYH10_RAT (2-612): 2.5e-23: 109: 12.42		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		496228 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		148818 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		149481 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PCLO_HUMAN (46-758): 3.43e-16: 85.9: 9.19
+	Dm
		1370269 BRE1_DROME (9-758): 2.45e-13: 76.6: 10.22		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96