HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: S100P (P25815)
Protein S100-P (Migration-inducing gene 9 protein) (MIG9) (Protein S100-E) (S100 calcium-binding protein P)
Gene: S100P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042803 - protein homodimerization activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 95
+	Hs
		638983 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		S100P_HUMAN (1-95): 3.03e-36: 119: 100.00
+	Hs
		638930 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S100P_HUMAN (1-95): 3.03e-36: 119: 100.00
+	Hs
		685160 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10AB_HUMAN (2-92): 1.47e-35: 118: 40.66
+	Hs
		615207 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10A1_HUMAN (2-93): 1.61e-35: 117: 53.26
+	Hs
		642921 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10A4_HUMAN (3-95): 3.19e-33: 112: 41.94
+	Hs
		661212 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10A2_HUMAN (2-95): 5.21e-32: 109: 40.43
+	Hs
		380748 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S100B_HUMAN (1-92): 1.7e-31: 107: 50.00
+	Hs
		707357 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10A3_HUMAN (3-93): 6.58e-30: 103: 32.97
+	Hs
		416584 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10A6_HUMAN (3-91): 5.01e-26: 93.8: 34.83
+	Hs
		707349 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10A5_HUMAN (2-94): 2.41e-24: 89.5: 36.56
+	Hs
		724898 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S1A7A_HUMAN (2-93): 2.03e-22: 84.9: 28.72
+	Hs
		678418 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10A7_HUMAN (2-93): 2.88e-21: 81.8: 26.60
+	Hs
		725028 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S10AE_HUMAN (2-83): 9.09e-21: 80.7: 25.61
+	Hs
		666670 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		S100G_HUMAN (6-83): 1.29e-19: 77.2: 35.90
+	Hs
		551768 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		HORN_HUMAN (1-92): 3.02e-34: 125: 34.78
+	Hs
		551730 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		FILA2_HUMAN (1-92): 2.45e-29: 111: 41.30
+	Hs
		148598 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		S10AA_HUMAN (2-89): 2.29e-30: 104: 44.32
+	Hs
		551847 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		S10AE_HUMAN (2-83): 9.09e-21: 80.7: 25.61