HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	37633270
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1001 Hs			1 126
+	Hs
		256269 BRE1B_HUMAN (1-1001): 5.92e-75: 268: 100.00		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		1087184 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		707654 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00
+	Mm
		1125390 BRE1A_MOUSE (1-1000): 4.02e-64: 236: 56.59		H2B1B_MOUSE (1-126): 5.1e-53: 164: 97.62
+	Sc
		356028 BRE1_YEAST (506-1000): 2.2e-57: 212: 18.77		H2B2_YEAST (3-125): 1.47e-40: 133: 70.73
+	Sc
		355667 BRE1_YEAST (506-1000): 2.2e-57: 212: 18.77		H2B1_YEAST (3-125): 4.34e-36: 121: 70.73
+	Hs
		1274476 MYH2_HUMAN (291-983): 3.18e-32: 138: 9.47		H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83
+	Hs
		724951 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83
+	Hs
		241463 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83
+	Hs
		724751 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62
+	Hs
		724734 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		H2B1D_HUMAN (1-126): 2.89e-54: 167: 97.62
+	Hs
		725214 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		H2B1H_HUMAN (1-126): 6.88e-55: 169: 96.83
+	Hs
		241464 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83
+	Hs
		725133 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62
+	Hs
		433154 LAMB1_HUMAN (82-412): 8.06e-19: 94.7: 12.65		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		725122 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		H2B1D_HUMAN (1-126): 2.89e-54: 167: 97.62
+	Hs
		241465 MYH11_HUMAN (563-983): 2.12e-18: 93.6: 10.66		H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83
+	Hs
		728463 MYH11_HUMAN (563-983): 2.12e-18: 93.6: 10.66		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62
+	Hs
		725231 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		H2B1L_HUMAN (1-126): 3.02e-53: 164: 96.03
+	Hs
		148194 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83