HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0042803 - protein homodimerization activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 248
+	Hs
		418976 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		451201 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16
+	Hs
		110796 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		H7BYY1_HUMAN (1-248): 8.1e-49: 162: 77.82
+	Hs
		418895 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		724765 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00
+	Hs
		434354 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39
+	Hs
		418844 LAMB1_HUMAN (82-412): 8.06e-19: 94.7: 12.65		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Dm
		404216 MYSA_DROME (2-686): 3.65e-25: 115: 10.22		TPM2_DROME (5-246): 7.24e-38: 135: 42.98
+	Hs
		148289 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		148661 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00