HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 2414
+	Hs
		724792 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		725147 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		256362 BRE1B_HUMAN (1-1001): 5.92e-75: 268: 100.00		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		725093 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89
+	Hs
		725074 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		725269 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		551867 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		724946 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		148838 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		148737 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86
+	Hs
		148818 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		149109 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86
+	Hs
		149481 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PCLO_HUMAN (533-1087): 8.45e-12: 73.6: 11.83