HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: FOXC1 (Q12948)
Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)
Gene: FOXC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34551306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 553
+	Hs
		1021122 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		724796 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		FOXO1_HUMAN (50-463): 3.5e-45: 171: 18.76
+	Hs
		725148 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		FOXO1_HUMAN (50-463): 3.5e-45: 171: 18.76
+	Hs
		528365 MYH6_HUMAN (461-982): 5.68e-20: 98.6: 9.77		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Hs
		551683 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		FOXO1_HUMAN (50-463): 3.5e-45: 171: 18.76
+	Hs
		126424 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		FOXE1_HUMAN (54-390): 3.86e-46: 167: 31.66
+	Hs
		551645 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		FOXA3_HUMAN (7-279): 3.13e-35: 137: 34.80