HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28515276, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 972
+	Hs
		1064396 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		724836 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		725165 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		148834 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		551710 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		148343 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		EF2_HUMAN (111-957): 0: 915: 38.16