HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 953
+	Hs
		724906 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		725197 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		256328 BRE1B_HUMAN (1-1001): 5.92e-75: 268: 100.00		MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24
+	Hs
		551764 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		724782 MYH9_HUMAN (271-982): 5.38e-32: 137: 10.53		ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63
+	Hs
		149481 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PCLO_HUMAN (54-952): 1.43e-31: 136: 7.21
+	Hs
		725139 MYH10_HUMAN (1-443): 3.14e-19: 96.3: 12.58		ANK2_HUMAN (498-952): 3.04e-11: 70.1: 14.63
+	Hs
		149078 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15
+	Hs
		149429 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		149035 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		551790 DESP_HUMAN (233-945): 1.26e-09: 64.9: 14.36		TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54
+	Hs
		148941 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		NIPBL_HUMAN (485-927): 6.3e-11: 68.9: 15.90
+	Hs
		148817 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		TRIPC_HUMAN (539-925): 2.98e-10: 66.6: 17.28
+	Hs
		148818 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73