HitPredict

Interactor 1: BRE1B (O75150)
E3 ubiquitin-protein ligase BRE1B (BRE1-B) (EC 2.3.2.27) (95 kDa retinoblastoma-associated protein) (RBP95) (RING finger protein 40) (RING-type E3 ubiquitin transferase BRE1B)
Gene: RNF40

Interactor 2: RB12B (Q8IXT5)
RNA-binding protein 12B (RNA-binding motif protein 12B)
Gene: RBM12B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 1001
+	Hs
		1138184 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		RB12B_HUMAN (1-1001): 0: 561: 100.00
+	Hs
		149031 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		RB12B_HUMAN (1-1001): 0: 561: 100.00
+	Sc
		633991 BRE1_YEAST (506-1000): 2.2e-57: 212: 18.77		GBP2_YEAST (157-454): 3.71e-47: 176: 15.61
+	Hs
		855092 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		HNRPF_HUMAN (274-503): 2.76e-38: 150: 20.25
+	Hs
		256352 BRE1B_HUMAN (1-1001): 5.92e-75: 268: 100.00		RBM12_HUMAN (1-87): 3.31e-19: 95.5: 72.41
+	Hs
		1138226 BRE1A_HUMAN (1-1000): 8.12e-65: 238: 56.49		RBM12_HUMAN (1-87): 3.31e-19: 95.5: 72.41
+	Hs
		148941 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		NIPBL_HUMAN (538-873): 7.39e-56: 214: 12.61
+	Hs
		148560 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		HNRPF_HUMAN (274-503): 2.76e-38: 150: 20.25
+	Hs
		148894 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PAP1L_HUMAN (3-269): 3.62e-28: 123: 11.40
+	Hs
		148691 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		TIAR_HUMAN (3-286): 4.25e-21: 98.6: 10.64
+	Hs
		148944 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		ESRP1_HUMAN (5-178): 1.58e-17: 89.7: 18.57
+	Hs
		148442 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		HNRH3_HUMAN (5-120): 1.83e-14: 78: 24.58
+	Hs
		148584 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		HNRH2_HUMAN (5-162): 7.84e-13: 73.8: 25.63
+	Hs
		148334 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PABP1_HUMAN (3-284): 4.43e-12: 72: 11.58
+	Hs
		149282 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PABP3_HUMAN (3-155): 6.53e-12: 71.6: 13.46
+	Hs
		148738 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		GRSF1_HUMAN (381-492): 5.51e-12: 71.2: 21.37
+	Hs
		149463 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		RBM19_HUMAN (285-575): 4.04e-11: 69.3: 11.59
+	Hs
		148763 CTRO_HUMAN (248-944): 2.51e-10: 67.2: 14.91		PABP4_HUMAN (3-156): 4.21e-11: 68.9: 11.11