HitPredict

Interactor 1: PHF2 (O75151)
Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2)
Gene: PHF2

Interactor 2: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1096 Hs			1 128
+	Hs
		555555 KDM2B_HUMAN (39-1055): 0: 735: 19.32		H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98
+	Hs
		555700 KDM2A_HUMAN (54-926): 0: 651: 19.24		H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98
+	Sp
		293757 JHD1_SCHPO (91-899): 7.69e-172: 531: 19.40		H2AZ_SCHPO (18-119): 1.91e-46: 148: 78.43
+	Hs
		555463 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98
+	Hs
		1312239 CXXC1_HUMAN (5-126): 2.47e-26: 117: 31.15		H2AJ_HUMAN (5-127): 8.35e-56: 171: 60.48
+	Hs
		1087121 CXXC1_HUMAN (5-126): 2.47e-26: 117: 31.15		H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29
+	Hs
		391942 CXXC1_HUMAN (5-126): 2.47e-26: 117: 31.15		H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48
+	Hs
		555671 CXXC1_HUMAN (5-126): 2.47e-26: 117: 31.15		H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98
+	Hs
		470008 BPTF_HUMAN (6-61): 1.51e-18: 94.2: 48.21		H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00
+	Hs
		1311990 DIDO1_HUMAN (5-92): 3.08e-20: 99.7: 30.44		H2AJ_HUMAN (5-127): 8.35e-56: 171: 60.48
+	Hs
		555434 BPTF_HUMAN (6-61): 1.51e-18: 94.2: 48.21		H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98
+	Sp
		815628 MSC1_SCHPO (5-133): 4.74e-24: 112: 20.93		H2AZ_SCHPO (18-119): 1.91e-46: 148: 78.43