HitPredict

Interactor 1: PHF2 (O75151)
Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2)
Gene: PHF2

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30554943
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1096 Hs			1 726
+	Hs
		1067196 PHF8_HUMAN (1-1096): 0: 903: 47.35		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		256383 PHF2_HUMAN (1-1096): 0: 919: 100.00		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		1356828 PHF8_HUMAN (1-1096): 0: 903: 47.35		BRPF3_HUMAN (37-484): 7.42e-31: 132: 14.82
+	Hs
		245098 PHF8_HUMAN (1-1096): 0: 903: 47.35		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		600258 PHF8_HUMAN (1-1096): 0: 903: 47.35		TAF1_HUMAN (23-303): 3.47e-17: 88.7: 13.52
+	Hs
		999234 KDM2A_HUMAN (54-926): 0: 651: 19.24		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		245112 KDM2A_HUMAN (54-926): 0: 651: 19.24		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Sp
		293809 JHD1_SCHPO (91-899): 7.69e-172: 531: 19.40		YK82_SCHPO (29-148): 6.59e-30: 128: 33.61
+	Sp
		293843 JHD1_SCHPO (91-899): 7.69e-172: 531: 19.40		BDF1_SCHPO (229-481): 1.08e-27: 120: 24.14
+	Sp
		293841 JHD1_SCHPO (91-899): 7.69e-172: 531: 19.40		GCN5_SCHPO (331-412): 7.79e-09: 60.5: 32.93
+	Hs
		1056838 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		631425 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		998710 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		999156 CXXC1_HUMAN (5-126): 2.47e-26: 117: 31.15		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Mm
		101451 FXL19_MOUSE (645-1070): 1.15e-24: 112: 14.25		F8VPR5_MOUSE (19-143): 9.58e-32: 135: 30.23
+	Hs
		244438 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Sc
		728742 SPP1_YEAST (4-133): 2.67e-28: 119: 21.33		BDF1_YEAST (191-693): 8.87e-19: 93: 14.43
+	Hs
		244869 DIDO1_HUMAN (5-92): 3.08e-20: 99.7: 30.44		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244354 BPTF_HUMAN (6-61): 1.51e-18: 94.2: 48.21		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Zm
		80272 B6TK34_MAIZE (5-59): 1.74e-25: 108: 30.91		K7TPV5_MAIZE (313-409): 1.51e-14: 79: 46.39