HitPredict

Interactor 1: PHF2 (O75151)
Lysine-specific demethylase PHF2 (EC 1.14.11.-) (GRC5) (PHD finger protein 2)
Gene: PHF2

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	30021884, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1096 Hs			1 126
+	Hs
		256396 PHF2_HUMAN (1-1096): 0: 919: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1087486 PHF8_HUMAN (1-1096): 0: 903: 47.35		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918535 KDM2B_HUMAN (39-1055): 0: 735: 19.32		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1087500 KDM2A_HUMAN (54-926): 0: 651: 19.24		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918780 KDM2A_HUMAN (54-926): 0: 651: 19.24		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1056847 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1056919 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		918364 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707631 MDC1_HUMAN (425-1089): 6.63e-30: 131: 12.88		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		918742 CXXC1_HUMAN (5-126): 2.47e-26: 117: 31.15		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		1087376 DIDO1_HUMAN (5-92): 3.08e-20: 99.7: 30.44		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		918650 DIDO1_HUMAN (5-92): 3.08e-20: 99.7: 30.44		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		241628 DIDO1_HUMAN (5-92): 3.08e-20: 99.7: 30.44		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		707733 DIDO1_HUMAN (5-92): 3.08e-20: 99.7: 30.44		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		1017308 BPTF_HUMAN (6-61): 1.51e-18: 94.2: 48.21		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		1017333 BPTF_HUMAN (6-61): 1.51e-18: 94.2: 48.21		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		918323 BPTF_HUMAN (6-61): 1.51e-18: 94.2: 48.21		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Sp
		392632 MSC1_SCHPO (5-133): 4.74e-24: 112: 20.93		H2B1_SCHPO (4-125): 1.24e-45: 145: 70.49
+	Sc
		355605 SPP1_YEAST (4-133): 2.67e-28: 119: 21.33		H2B1_YEAST (3-125): 1.81e-36: 122: 71.55