HitPredict

Interactor 1: RFIP3 (O75154)
Rab11 family-interacting protein 3 (FIP3) (FIP3-Rab11) (Rab11-FIP3) (Arfophilin-1) (EF hands-containing Rab-interacting protein) (Eferin) (MU-MB-17.148)
Gene: RAB11FIP3

Interactor 2: RB11B (Q15907)
Ras-related protein Rab-11B (EC 3.6.5.2) (GTP-binding protein YPT3)
Gene: RAB11B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	11495908
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	GO:0005829 - cytosol GO:0032456 - endocytic recycling GO:0055037 - recycling endosome GO:0055038 - recycling endosome membrane GO:2001135 - regulation of endocytic recycling
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 756 Hs			1 218
+	Hs
		256700 RFIP3_HUMAN (1-756): 1.9e-149: 456: 100.00		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		256698 RFIP3_HUMAN (1-756): 1.9e-149: 456: 100.00		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Dm
		185688 Q8SYQ0_DROME (420-756): 4.77e-52: 190: 28.77		O18335_DROME (1-216): 4.19e-87: 257: 83.80
+	Dm
		185677 Q6NN29_DROME (460-756): 8.17e-50: 185: 29.90		O18335_DROME (1-216): 4.19e-87: 257: 83.80
+	Hs
		1079939 RFIP4_HUMAN (194-756): 1.08e-34: 142: 34.91		RB11B_HUMAN (1-218): 2.77e-95: 278: 100.00
+	Hs
		914190 RFIP4_HUMAN (194-756): 1.08e-34: 142: 34.91		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		914003 TMF1_HUMAN (316-755): 1.58e-27: 121: 17.49		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		884470 TMF1_HUMAN (316-755): 1.58e-27: 121: 17.49		RAB25_HUMAN (2-218): 1.3e-83: 249: 60.63
+	Hs
		148636 CTRO_HUMAN (192-754): 3.76e-21: 101: 9.85		RAB1A_HUMAN (1-215): 2.92e-90: 265: 43.26
+	Hs
		149274 CTRO_HUMAN (192-754): 3.76e-21: 101: 9.85		RAB1B_HUMAN (4-215): 8.36e-87: 256: 44.81
+	Hs
		914383 MYO5C_HUMAN (390-756): 7.11e-17: 87.5: 11.83		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		914124 MRCKA_HUMAN (189-633): 1.56e-16: 86.8: 10.54		RB11A_HUMAN (1-218): 1.25e-91: 269: 90.37
+	Hs
		895035 TMF1_HUMAN (316-755): 1.58e-27: 121: 17.49		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895213 MY18A_HUMAN (322-756): 1.34e-19: 96.4: 11.24		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895123 MRCKA_HUMAN (189-633): 1.56e-16: 86.8: 10.54		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56
+	Hs
		895077 DCTN1_HUMAN (427-690): 2.8e-10: 66: 13.94		RAB2A_HUMAN (8-178): 5.89e-61: 191: 55.56