HitPredict

Interactor 1: CAND2 (O75155)
Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (Epididymis tissue protein Li 169) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2)
Gene: CAND2

Interactor 2: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1236 Hs			1 458
+	Hs
		658256 CAND1_HUMAN (1-1236): 0: 845: 62.09		5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00
+	Hs
		256737 CAND2_HUMAN (1-1236): 0: 832: 100.00		5HT6R_HUMAN (30-416): 1.47e-64: 216: 25.71
+	Hs
		658240 Q4LE60_HUMAN (396-1168): 3.68e-35: 147: 11.49		5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00
+	Hs
		155535 TNPO2_HUMAN (427-1168): 2.37e-33: 141: 11.48		5HT2C_HUMAN (1-458): 1.97e-103: 317: 100.00
+	Mm
		1337542 MTOR_MOUSE (15-1059): 3.9e-43: 174: 13.56		5HT6R_MOUSE (56-405): 5.69e-78: 251: 26.71
+	Hs
		787421 MTOR_HUMAN (15-1059): 7.2e-43: 174: 13.64		5HT6R_HUMAN (30-416): 1.47e-64: 216: 25.71
+	Hs
		839279 TNPO1_HUMAN (644-1188): 2.85e-21: 102: 12.74		5HT6R_HUMAN (30-416): 1.47e-64: 216: 25.71