HitPredict

Interactor 1: PP6R2 (O75170)
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)
Gene: PPP6R2

Interactor 2: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 966 Hs			1 937
+	Hs
		257175 PP6R2_HUMAN (1-966): 0: 893: 100.00		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		925891 PP6R3_HUMAN (1-914): 0: 746: 46.31		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		1014025 PP6R3_HUMAN (1-914): 0: 746: 46.31		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		926056 PP6R1_HUMAN (1-898): 0: 640: 39.94		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		257152 PP6R2_HUMAN (1-966): 0: 893: 100.00		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Hs
		212577 PP6R2_HUMAN (1-966): 0: 893: 100.00		AP1G1_HUMAN (11-808): 1.03e-173: 527: 17.57
+	Hs
		321563 PP6R3_HUMAN (1-914): 0: 746: 46.31		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Hs
		302165 PP6R3_HUMAN (1-914): 0: 746: 46.31		AP2A2_HUMAN (11-933): 0: 600: 16.99
+	Hs
		203219 SYNJ1_HUMAN (399-965): 5.49e-29: 127: 10.15		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		203223 SYNJ1_HUMAN (399-965): 5.49e-29: 127: 10.15		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		203194 SYNJ1_HUMAN (399-965): 5.49e-29: 127: 10.15		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Rn
		1144064 SYNJ1_RAT (399-965): 1.33e-30: 132: 11.27		Q66HM2_RAT (11-932): 0: 590: 16.38