Interactor 1: ATS4 (O75173)
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4) (EC 3.4.24.82) (ADMP-1) (Aggrecanase-1)
Gene: ADAMTS4

Interactor 2: ATS2 (O95450)
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI)
Gene: ADAMTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ADAMTS_CR_2~ADAMTS_CR_2, ADAMTS_CR_2~Reprolysin, ADAMTS_CR_2~TSP_1, ADAMTS_CR_3~ADAMTS_spacer1, ADAMTS_CR_3~TSP_1, Reprolysin~Reprolysin, TSP_1~TSP_1
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0005576 - extracellular region
GO:0008237 - metallopeptidase activity
GO:0008270 - zinc ion binding
GO:0030198 - extracellular matrix organization
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 837
Hs

1 1211
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024