Interactor 1: ATS4 (O75173)
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAM-TS 4) (ADAM-TS4) (ADAMTS-4) (EC 3.4.24.82) (ADMP-1) (Aggrecanase-1)
Gene: ADAMTS4

Interactor 2: ADA21 (Q9UKJ8)
Disintegrin and metalloproteinase domain-containing protein 21 (ADAM 21) (EC 3.4.24.-)
Gene: ADAM21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ADAMTS_CR_2~Reprolysin, ADAM_CR~Reprolysin, Disintegrin~Reprolysin, Reprolysin~Reprolysin
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0006508 - proteolysis
GO:0008237 - metallopeptidase activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 837
Hs

1 722
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Last updated: 15 Jul 2024