HitPredict

Interactor 1: CNOT3 (O75175)
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)
Gene: CNOT3

Interactor 2: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 753 Hs			1 550
+	Hs
		1052272 CTTB2_HUMAN (33-686): 6.31e-57: 213: 14.86		SRC8_HUMAN (1-550): 0: 559: 100.00
+	Hs
		1052340 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		SRC8_HUMAN (1-550): 0: 559: 100.00
+	Hs
		203224 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01
+	Hs
		203262 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		PACN2_HUMAN (176-550): 4.93e-40: 153: 15.37
+	Mm
		88459 D3Z656_MOUSE (145-672): 5.24e-43: 170: 14.98		SH3G2_MOUSE (365-549): 4.6e-31: 125: 17.80
+	Mm
		88460 D3Z656_MOUSE (145-672): 5.24e-43: 170: 14.98		SH3G3_MOUSE (365-549): 4.53e-31: 125: 19.89
+	Hs
		203251 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		PACN1_HUMAN (241-549): 2.37e-31: 128: 16.86
+	Hs
		203249 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		SH3G2_HUMAN (365-549): 1.87e-31: 126: 17.28
+	Hs
		203248 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		SH3G1_HUMAN (365-549): 6.52e-31: 125: 17.01
+	Hs
		203228 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99
+	Hs
		203191 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		VINEX_HUMAN (254-546): 4.43e-13: 73.9: 13.51
+	Hs
		203192 SYNJ1_HUMAN (145-672): 1.73e-35: 147: 13.59		SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91
+	Rn
		192356 SYNJ1_RAT (134-582): 2.65e-16: 85.9: 13.97		SH3G3_RAT (365-549): 5.6e-32: 128: 19.36
+	Rn
		193638 SYNJ1_RAT (134-582): 2.65e-16: 85.9: 13.97		SH3G1_RAT (365-549): 1.58e-31: 127: 17.01
+	Rn
		192354 SYNJ1_RAT (134-582): 2.65e-16: 85.9: 13.97		SH3G2_RAT (365-549): 8.86e-31: 124: 17.28
+	Hs
		166056 SYNJ2_HUMAN (145-642): 7.85e-25: 113: 15.01		ITSN2_HUMAN (398-548): 1.14e-18: 92.3: 17.88
+	Hs
		166049 SYNJ2_HUMAN (145-642): 7.85e-25: 113: 15.01		ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99
+	Rn
		192744 SYNJ1_RAT (134-582): 2.65e-16: 85.9: 13.97		SRBS2_RAT (452-549): 1.44e-11: 69.6: 22.00
+	Hs
		1078907 PTN23_HUMAN (331-666): 2.21e-09: 63.2: 13.02		ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99
+	Hs
		1270618 PTN23_HUMAN (331-666): 2.21e-09: 63.2: 13.02		STAM1_HUMAN (416-546): 2.82e-13: 74.4: 21.83