HitPredict

Interactor 1: CNOT3 (O75175)
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)
Gene: CNOT3

Interactor 2: MINK1 (Q8N4C8)
Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
Gene: MINK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 753 Hs			1 1332
+	Hs
		1233554 CNOT2_HUMAN (245-750): 4.42e-34: 139: 18.66		MINK1_HUMAN (1-1332): 0: 1277: 100.00
+	Hs
		1233557 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		MINK1_HUMAN (1-1332): 0: 1277: 100.00
+	Mm
		56843 TANC2_MOUSE (6-666): 1.16e-52: 200: 14.68		TNIK_MOUSE (1-1332): 0: 1112: 62.60
+	Hs
		1264914 CTTB2_HUMAN (33-686): 6.31e-57: 213: 14.86		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Hs
		1335966 TANC2_HUMAN (6-666): 1.29e-56: 212: 15.13		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Mm
		82720 CTTB2_MOUSE (36-686): 1.11e-45: 179: 13.99		TNIK_MOUSE (1-1332): 0: 1112: 62.60
+	Hs
		324853 CTTB2_HUMAN (33-686): 6.31e-57: 213: 14.86		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		324887 TANC2_HUMAN (6-666): 1.29e-56: 212: 15.13		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		1350214 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Hs
		1356429 PCLO_HUMAN (227-606): 2.65e-11: 69.6: 19.40		TNIK_HUMAN (1-1332): 0: 1098: 60.83
+	Hs
		324896 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		M4K4_HUMAN (1-1332): 0: 1026: 57.14
+	Hs
		131594 CTTB2_HUMAN (33-686): 6.31e-57: 213: 14.86		STK25_HUMAN (20-413): 1.71e-119: 380: 37.37
+	Hs
		1264921 CTTB2_HUMAN (33-686): 6.31e-57: 213: 14.86		STK24_HUMAN (20-443): 5.39e-117: 374: 34.98
+	Hs
		1264911 CTTB2_HUMAN (33-686): 6.31e-57: 213: 14.86		STK26_HUMAN (16-413): 5.32e-114: 365: 37.00
+	Hs
		1027448 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		STK3_HUMAN (3-507): 3.96e-120: 384: 30.12
+	Hs
		1023131 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		STK4_HUMAN (5-469): 5.1e-119: 381: 32.99
+	Hs
		131617 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		STK25_HUMAN (20-413): 1.71e-119: 380: 37.37
+	Hs
		1350219 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		STK24_HUMAN (20-443): 5.39e-117: 374: 34.98
+	Hs
		1350176 CT2NL_HUMAN (38-523): 2.51e-30: 129: 11.72		STK26_HUMAN (16-413): 5.32e-114: 365: 37.00
+	Hs
		1329363 PTN23_HUMAN (331-666): 2.21e-09: 63.2: 13.02		SLK_HUMAN (20-809): 1.86e-122: 413: 22.98