HitPredict

Interactor 1: CNOT3 (O75175)
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)
Gene: CNOT3

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	21984185, 21981923, 28813667, 29395067
Identification Methods	pull down, affinity chromatography technology, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 753 Hs			1 1962
+	Hs
		1242674 CNOT2_HUMAN (245-750): 4.42e-34: 139: 18.66		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Hs
		257428 CNOT3_HUMAN (1-753): 1.27e-150: 459: 100.00		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		257413 CNOT3_HUMAN (1-753): 1.27e-150: 459: 100.00		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Hs
		1242603 KMT2C_HUMAN (112-683): 5.89e-12: 72: 8.86		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Hs
		257662 ANR17_HUMAN (221-661): 3.32e-09: 62.7: 13.54		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Mm
		1206839 CNOT3_MOUSE (1-753): 1.21e-147: 451: 94.42		TNR6B_MOUSE (44-1944): 1.45e-146: 501: 31.87
+	Hs
		1349348 CNOT2_HUMAN (245-750): 4.42e-34: 139: 18.66		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		1336203 CNOT2_HUMAN (245-750): 4.42e-34: 139: 18.66		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Dm
		1178903 Q7K126_DROME (1-752): 3.14e-121: 385: 34.12		GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88
+	Hs
		1330361 PTN23_HUMAN (331-666): 2.21e-09: 63.2: 13.02		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		257704 ANR17_HUMAN (221-661): 3.32e-09: 62.7: 13.54		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Mm
		101458 CNOT3_MOUSE (1-753): 1.21e-147: 451: 94.42		F8VPR5_MOUSE (735-1757): 5.22e-19: 96.7: 10.60
+	Hs
		257347 CNOT3_HUMAN (1-753): 1.27e-150: 459: 100.00		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Dm
		1249007 RGA_DROME (324-749): 7.27e-25: 111: 16.08		GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88
+	Dm
		1370333 Q9VLS7_DROME (251-642): 1.76e-11: 70.4: 19.13		Q9VXR3_DROME (1321-1891): 6.42e-39: 162: 13.36
+	Hs
		554259 MUC1_HUMAN (183-644): 3.98e-20: 98.2: 12.88		MUC1_HUMAN (845-1740): 1.98e-15: 84.9: 11.69
+	Hs
		1170076 SRCAP_HUMAN (261-645): 5.18e-11: 68.8: 20.00		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		554303 MUC1_HUMAN (183-644): 3.98e-20: 98.2: 12.88		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		998826 SRCAP_HUMAN (261-645): 5.18e-11: 68.8: 20.00		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Dm
		113976 M9PB30_DROME (302-673): 2.29e-09: 63.5: 12.21		M9PB30_DROME (58-812): 9.58e-09: 63.2: 8.52