HitPredict

Interactor 1: CNOT3 (O75175)
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)
Gene: CNOT3

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 23663784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 753 Hs			1 1191
+	Hs
		257363 CNOT3_HUMAN (1-753): 1.27e-150: 459: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1335209 CNOT2_HUMAN (245-750): 4.42e-34: 139: 18.66		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		257703 ANR17_HUMAN (221-661): 3.32e-09: 62.7: 13.54		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Dm
		1178912 Q7K126_DROME (1-752): 3.14e-121: 385: 34.12		Q9VV48_DROME (1-615): 0: 665: 48.76
+	Hs
		1136333 CNOT2_HUMAN (245-750): 4.42e-34: 139: 18.66		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		257623 ANR17_HUMAN (221-661): 3.32e-09: 62.7: 13.54		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Dm
		1276861 RGA_DROME (324-749): 7.27e-25: 111: 16.08		Q9VV48_DROME (1-615): 0: 665: 48.76
+	Hs
		257299 CNOT3_HUMAN (1-753): 1.27e-150: 459: 100.00		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Mm
		101458 CNOT3_MOUSE (1-753): 1.21e-147: 451: 94.42		F8VPR5_MOUSE (603-1040): 1.87e-10: 67.7: 8.22
+	Hs
		257714 CNOT2_HUMAN (245-750): 4.42e-34: 139: 18.66		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		554259 MUC1_HUMAN (183-644): 3.98e-20: 98.2: 12.88		MUC1_HUMAN (344-901): 6.29e-21: 102: 9.70
+	Hs
		1336185 MAGE1_HUMAN (234-587): 3.65e-13: 75.4: 18.80		MAGE1_HUMAN (459-823): 2.66e-11: 70.3: 14.21
+	Mm
		1351630 PCLO_MOUSE (100-689): 8.31e-09: 61.6: 8.49		PCLO_MOUSE (522-1015): 6.21e-15: 82.8: 8.09
+	Dm
		375663 Q9VLS7_DROME (251-642): 1.76e-11: 70.4: 19.13		RPB1_DROME (644-998): 4.65e-09: 63.1: 10.28
+	Hs
		1170076 SRCAP_HUMAN (261-645): 5.18e-11: 68.8: 20.00		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Dm
		113976 M9PB30_DROME (302-673): 2.29e-09: 63.5: 12.21		M9PB30_DROME (683-1171): 5.39e-11: 69.7: 12.25