Interactor 1: CNOT3 (O75175)
CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3) (Leukocyte receptor cluster member 2)
Gene: CNOT3

Interactor 2: CNOT2 (Q9NZN8)
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)
Gene: CNOT2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 16778766, 16189514, 26496610, 29395067, 32296183, 33961781, 21984185, unassigned1304, 20211142, 31515488
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, anti bait coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains NOT2_3_5~NOT2_3_5
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000932 - P-body
GO:0001829 - trophectodermal cell differentiation
GO:0005634 - nucleus
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 753
Hs

1 540
+ Mm
+ Dm
+ Ce
+ Hs
+ Ce
+ Ce
+ Hs
+ Sc
+ Ce
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs
+ Dm

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Last updated: 15 Jul 2024