HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: ACL6A (O96019)
Actin-like protein 6A (53 kDa BRG1-associated factor A) (Actin-related protein Baf53a) (ArpNbeta) (BRG1-associated factor 53A) (BAF53A) (INO80 complex subunit K)
Gene: ACTL6A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 429
+	Hs
		296446 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ACL6B_HUMAN (1-429): 0: 762: 83.45
+	Hs
		296493 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		ACL6B_HUMAN (1-429): 0: 762: 83.45
+	Mm
		1150293 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		ACL6B_MOUSE (1-429): 0: 753: 82.52
+	Hs
		296435 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ACL6B_HUMAN (1-429): 0: 762: 83.45
+	Mm
		1111963 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		ACL6B_MOUSE (1-429): 0: 753: 82.52
+	Hs
		331517 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ACL6A_HUMAN (1-429): 0: 597: 100.00
+	Hs
		257462 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		ACTC_HUMAN (5-428): 0: 547: 34.67
+	Hs
		891783 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ACTB_HUMAN (9-428): 0: 553: 34.29
+	Hs
		929872 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ACTG_HUMAN (9-428): 0: 553: 34.29
+	Hs
		932179 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ACTC_HUMAN (5-428): 0: 547: 34.67
+	Hs
		60090 A4PIV7_HUMAN (1-388): 2.74e-63: 212: 52.93		ACTB_HUMAN (9-428): 0: 553: 34.29
+	Mm
		1150300 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		ACL6A_MOUSE (1-429): 0: 595: 98.83
+	Hs
		331611 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		ACL6A_HUMAN (1-429): 0: 597: 100.00
+	Hs
		331473 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ACL6A_HUMAN (1-429): 0: 597: 100.00
+	Mm
		929795 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		ACTG_MOUSE (9-428): 0: 553: 34.29
+	Hs
		846742 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ACTC_HUMAN (5-428): 0: 547: 34.67
+	Xl
		292752 Q4VQ79_XENLA (141-379): 1.01e-13: 75.1: 13.81		ACTB_XENLA (9-428): 0: 553: 34.29
+	Mm
		929785 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		ACTG_MOUSE (9-428): 0: 553: 34.29
+	At
		97194 EAF1A_ARATH (48-377): 7.43e-36: 141: 14.44		ARP4_ARATH (5-429): 2.43e-125: 372: 41.74
+	At
		97192 F4J7T1_ARATH (48-377): 4.15e-30: 124: 13.90		ARP4_ARATH (5-429): 2.43e-125: 372: 41.74