HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 396 Hs			1 464
+	Hs
		379441 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		257440 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		346865 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		379141 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379142 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379162 SC24C_HUMAN (134-389): 2.67e-09: 61.2: 15.97		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		379973 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00
+	Hs
		346267 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Mm
		348422 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		MYC_MOUSE (5-463): 1.09e-71: 235: 33.95
+	Hs
		346268 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		346316 SC24C_HUMAN (134-389): 2.67e-09: 61.2: 15.97		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		348113 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		MYC_HUMAN (7-463): 5.91e-69: 228: 34.16
+	Hs
		738947 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25
+	Hs
		738948 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		SRBP1_HUMAN (86-464): 8.15e-36: 143: 14.25
+	Mm
		1111973 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		SRBP1_MOUSE (91-464): 8.46e-31: 128: 16.80
+	Dm
		113976 M9PB30_DROME (92-352): 1.62e-11: 68.5: 12.23		M9PB30_DROME (40-373): 1.28e-09: 62.9: 8.08