HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: ERG (P11308)
Transcriptional regulator ERG (Transforming protein ERG)
Gene: ERG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 479
+	Hs
		507433 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ERG_HUMAN (1-479): 0: 611: 100.00
+	Hs
		965404 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		FLI1_HUMAN (1-479): 0: 518: 63.22
+	Hs
		507385 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ERG_HUMAN (1-479): 0: 611: 100.00
+	Hs
		507386 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		ERG_HUMAN (1-479): 0: 611: 100.00
+	Hs
		507518 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		ERG_HUMAN (1-479): 0: 611: 100.00
+	Hs
		846751 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		FLI1_HUMAN (1-479): 0: 518: 63.22
+	Hs
		846934 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		FLI1_HUMAN (1-479): 0: 518: 63.22
+	Hs
		257517 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		FEV_HUMAN (269-479): 3.91e-62: 204: 47.06
+	Hs
		794541 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		ETV4_HUMAN (188-445): 1.34e-58: 202: 25.27
+	Hs
		257447 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		ETS1_HUMAN (119-311): 2.34e-29: 121: 21.13
+	Mm
		542772 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		ETS2_MOUSE (2-409): 8.52e-79: 254: 25.71
+	Hs
		794530 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ETV4_HUMAN (188-445): 1.34e-58: 202: 25.27
+	Hs
		846856 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ELF4_HUMAN (150-466): 9.28e-56: 198: 21.61
+	Hs
		1350248 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		ETV7_HUMAN (89-394): 9.29e-72: 232: 26.28
+	Hs
		692114 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ELF1_HUMAN (215-475): 4.57e-48: 176: 22.88
+	Hs
		1304713 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		FEV_HUMAN (269-479): 3.91e-62: 204: 47.06
+	Hs
		541992 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		ETS1_HUMAN (119-311): 2.34e-29: 121: 21.13
+	Hs
		785417 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		ELK3_HUMAN (325-464): 1.74e-47: 170: 37.14
+	Hs
		781237 CHD7_HUMAN (39-357): 2.97e-09: 61.2: 11.83		ETV3_HUMAN (299-477): 3e-44: 164: 40.22
+	Hs
		541993 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		ETS1_HUMAN (119-311): 2.34e-29: 121: 21.13