HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: SMCA2 (P51531)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (hBRM) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: SMARCA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31753913, 24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:0071565 - nBAF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 1590
+	Hs
		846783 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Mm
		1150290 CREST_MOUSE (1-396): 4.64e-78: 248: 89.80		SMCA2_MOUSE (1-1590): 0: 1055: 94.38
+	Hs
		60100 A4PIW0_HUMAN (1-342): 3.78e-54: 187: 47.65		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Mm
		1111948 CREST_MOUSE (1-396): 4.64e-78: 248: 89.80		SMCA4_MOUSE (40-1588): 0: 986: 72.81
+	Hs
		257459 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		846890 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		SMCA2_HUMAN (1-1590): 0: 1088: 100.00
+	Mm
		1111934 SSXT_MOUSE (1-396): 7.26e-71: 230: 56.22		SMCA4_MOUSE (40-1588): 0: 986: 72.81
+	Rn
		88986 D4ABC5_RAT (1-396): 7.22e-70: 227: 56.22		SMCA4_RAT (40-1588): 0: 986: 72.87
+	Hs
		846980 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		60089 A4PIV7_HUMAN (1-388): 2.74e-63: 212: 52.93		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		60096 A4PIV9_HUMAN (1-388): 2.68e-63: 212: 52.93		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Mm
		1111937 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		SMCA4_MOUSE (40-1588): 0: 986: 72.81
+	Hs
		847108 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Hs
		846723 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMCA4_HUMAN (40-1588): 0: 977: 72.70
+	Mm
		1111917 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		SMCA4_MOUSE (40-1588): 0: 986: 72.81
+	Hs
		229409 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	Hs
		60097 A4PIW0_HUMAN (1-342): 3.78e-54: 187: 47.65		SMCA5_HUMAN (610-1584): 0: 803: 27.43
+	Hs
		846775 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		CHD4_HUMAN (370-1589): 0: 749: 22.31
+	Hs
		846763 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		CHD3_HUMAN (415-1590): 0: 725: 23.92
+	Mm
		57185 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		CHD7_MOUSE (79-693): 1.13e-14: 82.1: 9.19