HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0003713 - transcription coactivator activity GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0071565 - nBAF complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 396 Hs			1 1214
+	Hs
		1074751 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		257509 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		1074759 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		60093 A4PIV7_HUMAN (1-388): 2.74e-63: 212: 52.93		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		1251642 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		846825 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Mm
		1150284 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		SMRC2_MOUSE (1-1203): 0: 957: 96.51
+	Hs
		1272958 S18L2_HUMAN (1-73): 9.86e-40: 137: 60.27		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Mm
		956819 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		SMRC1_MOUSE (4-1028): 0: 952: 64.13
+	Hs
		846839 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Mm
		1111940 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		SMRC2_MOUSE (1-1203): 0: 957: 96.51
+	Mm
		956808 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		SMRC1_MOUSE (4-1028): 0: 952: 64.13
+	Hs
		159804 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		3232 CREST_HUMAN (1-396): 3.15e-78: 248: 100.00		A0A0S2Z4Q4_HUMAN (748-1181): 4.67e-43: 170: 19.11
+	Mm
		1149043 SMCA2_MOUSE (74-384): 6.58e-36: 142: 17.93		MYSM1_MOUSE (276-523): 3.33e-50: 194: 19.16
+	Mm
		1111936 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		MYSM1_MOUSE (276-523): 3.33e-50: 194: 19.16
+	Hs
		232058 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Mm
		1351630 PCLO_MOUSE (72-312): 1.26e-13: 75.1: 15.35		PCLO_MOUSE (643-1196): 2.88e-11: 70.5: 9.26
+	Mm
		57185 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		CHD7_MOUSE (856-1214): 3.35e-12: 73.5: 11.26
+	Dm
		113976 M9PB30_DROME (92-352): 1.62e-11: 68.5: 12.23		M9PB30_DROME (665-1213): 3.26e-09: 63.9: 9.40