HitPredict

Interactor 1: CREST (O75177)
Calcium-responsive transactivator (SS18-like protein 1) (SYT homolog 1)
Gene: SS18L1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016358 - dendrite development GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 396 Hs			1 488
+	Hs
		1074755 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		60105 A4PIW0_HUMAN (1-342): 3.78e-54: 187: 47.65		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Mm
		140279 SSXT_MOUSE (1-396): 7.26e-71: 230: 56.22		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		1038405 SSXT_HUMAN (1-396): 5.46e-68: 222: 53.83		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		60102 A4PIW0_HUMAN (1-342): 3.78e-54: 187: 47.65		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		846833 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		847037 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Mm
		936385 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		HDAC2_MOUSE (1-488): 0: 704: 99.39
+	Hs
		846768 SMCA2_HUMAN (74-384): 1.05e-26: 114: 15.67		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		140261 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		HDAC1_MOUSE (1-443): 0: 645: 90.29
+	Hs
		846962 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Mm
		292413 SMCA4_MOUSE (74-384): 3.38e-11: 67.4: 12.96		HDAC3_MOUSE (10-431): 0: 574: 58.49
+	Hs
		177241 SMCA4_HUMAN (74-338): 1.2e-10: 65.5: 11.08		HDAC3_HUMAN (10-431): 0: 574: 58.26